Friday, May 4, 2018

Veterinary Highlights: Is Cure for IMHA Near?

Immune-mediated hemolytic anemia (IMHA) is the most common immune-mediated disease affecting dogs. It's a horrible disease in which the immune system attacks red blood cells and destroys them. Some dogs survive and some succumb to the disease in spite of treatment.

There isn't much of warning; the disease hits hard and fast. There isn't much prevention either; anything that triggers the immune system. More needs to be done to determine genetic disposition and triggers.

Veterinarians are making progress in researching the genetic and environmental factors putting dogs at risk.

The typical treatment for IMHA includes immunosuppressive drugs, medications to prevent clotting, and blood transfusions.

"Dogs have narrow therapeutic windows. The gaps between effective, ineffective, and dangerous drug doses are really narrow.”

Researchers are working on blood analysis techniques and identifying biomarkers to achieve safer dosing and more targetted treatment.

One promising new treatment is plasmapherisis, also known as therapeutic plasma exchange. The idea is to separate plasma and cells and transfuse the cells back into the bloodstream with removed antibodies. Trial results have been promising.

Source article:
Is a Cure for IMHA near?

Related articles:
Symptoms to Watch for in Your Dog: Pale Gums
Dr. Jekyll and Mr. Hyde: Razzle's IMHA
I am an IMHA Survivor: Dylan's Story
IMHA Complications: Daphne Didn't Make It
IMHA Survivor: Pete's Story
IMHA: Nikki's Story

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