Friday, October 11, 2013

Veterinary Highlights: Adverse Drug Reactions In Pets

We'll never know how and why morphine became Jasmine's worst enemy. All we know that it somehow played a major role at the way things played out.

Jasmine's system was sensitive to other drugs as well, including NSAIDs and buprenorphine. Morphine, though, has always been her ally, until it was not.

A lack of awareness of drug hypersensitivity reactions in the veterinary field has led to an underestimation of their severity and frequency. 

Dr. Sidonie Lavergne, a faculty member at the University of Illinois College of Veterinary Medicine, an expert in veterinary pharmacology, toxicology, and the immune system,  is spearheading an investigation into the nature and occurrence of allergic events, focusing on both dogs and humans.

In both humans and pet species, allergic reactions can manifest in a variety of ways.

Most drug allergic reactions are not immediate but rather require days, sometimes months, of drug exposure before onset.

Dr. Lavergne can test for the presence of drug-specific memory T cells and small molecules recognizing the drug (antibodies) in a pet’s blood sample.

Testing can be done not only to treat current patients but also reevaluate past cases where drug allergy was never confirmed.

How often might drugs be your dog's enemy, instead of an ally? And how often this might get missed?

Source article:
Expert Seeks to Expand Knowledge of Adverse Drug Reactions in Pets

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