Having a problem with dry eye (keratoconjunctivitis sicca) myself, I can relate to how unpleasant it is. It turns out it is quite common in dogs and besides discomfort it can also lead to loss of vision.
US Davis is running an exciting clinical study on the use of mesenchymal stem cell therapy for the treatment of dry eye in dogs.
That is even more exciting, because we have direct experience using stem cell therapy for Jasmine, both for her arthritis and IBD. Same type, stem cells derived from the patient's own fat tissue.
Mesenchymal stem cells (MSCs) have been proven to reduce inflammation and differentiate into a variety of cell types. Since the most common cause of dry eye in dogs is an immune-mediated inflammatory response targeted against tear producing glands, this study was designed to determine if treatment with MSCs will cause local, long term control of tear gland inflammation and dry eye.
The harvested stem cells will be injected into the tear producing glands.
If the stem cell treatment of dogs with immune-mediated dry eye results in increased tear production, it might eliminate the need for life-long topical medications.
I don't know about your dog, but Jasmine HATED getting eye drops.
The study covers the examinations, medications and study procedures; there is no cost to the owner.
For details contact Monica Motta (530) 752-0926, firstname.lastname@example.org
UC Davis Veterinary Medicine Clinical Studies